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1.
Epidermal Growth Factor Receptor Inhibitors in Glioblastoma: Current Status and Future Possibilities.
Int J Mol Sci
; 25(4)2024 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38396993
2.
Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain.
Mol Cell Biochem
; 2023 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37922111
3.
Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration.
Metab Brain Dis
; 37(1): 147-152, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34347206
4.
Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases.
Int J Mol Sci
; 23(24)2022 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36555098
5.
Computational and in vitro characterization of ICY-5: A potential candidate promoting mitochondrial apoptosis via the c-MET and STAT3 pathways.
J Cell Physiol
; 236(1): 146-156, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32484605
6.
Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease.
Bioorg Med Chem
; 45: 116311, 2021 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34304133
7.
FCX-146, a potent allosteric inhibitor of Akt kinase in cancer cells: Lead optimization of the second-generation arylidene indanone scaffold.
Biotechnol Appl Biochem
; 68(1): 82-91, 2021 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-32067263
8.
Interleukin-1ß drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site.
J Neuroinflammation
; 16(1): 275, 2019 Dec 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31882005
9.
A novel tetrazole analogue of resveratrol is a potent anticancer agent.
Bioorg Med Chem Lett
; 29(2): 172-178, 2019 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30528695
10.
Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs.
Alzheimers Dement
; 14(2): 230-242, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28945989
11.
Leave-one-out-analysis (LOOA): web-based tool to predict influential proteins and interactions in aggregate-crosslinking proteomic data.
Bioinformation
; 20(1): 4-10, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38352912
12.
Alzheimer's-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets.
iScience
; 27(1): 108745, 2024 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38274404
13.
Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer's disease by targeted small molecules.
Commun Biol
; 7(1): 60, 2024 01 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38191671
14.
In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration.
Sci Rep
; 13(1): 2096, 2023 02 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36747013
15.
Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan.
Pharmaceuticals (Basel)
; 16(10)2023 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37895969
16.
Machine-learning analysis of intrinsically disordered proteins identifies key factors that contribute to neurodegeneration-related aggregation.
Front Aging Neurosci
; 14: 938117, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35992603
17.
Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer's Disease.
Pharmaceutics
; 14(7)2022 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-35890250
18.
"Protein aggregates" contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation.
Aging Cell
; 20(5): e13326, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33788386
19.
Antitumor properties of novel sesquiterpene lactone analogs as NFκB inhibitors that bind to the IKKß ubiquitin-like domain (ULD).
Eur J Med Chem
; 224: 113675, 2021 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34229108
20.
Computational target-based drug repurposing of elbasvir, an antiviral drug predicted to bind multiple SARS-CoV-2 proteins.
ChemRxiv
; 2020 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32511290